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High Concentration Oxygen for Pneumocephalus After Evacuation of Chronic Subdural Haematoma

NCT04725851 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2022-07-28

No results posted yet for this study

Summary

Normobaric oxygen therapy was shown to be effective in reducing post craniotomy pneumocephalus. Theoretical assessment of normobaric oxygen therapy in treating pneumocephalus has shown that a higher level of oxygen concentration will significantly decrease the time for absorption of pneumocephalus. The therapeutic efficacy is not fully established in patients with chronic subdural hematoma after burr hole drainage. Both radiological outcomes and clinical outcomes would be evaluated.

Conditions

  • Chronic Subdural Hematoma
  • Recurrence
  • Oxycephaly

Interventions

PROCEDURE

High concentration Oxygen therapy

FiO2 \>80% Oxygen (Delivered with 12-15L/min Non-rebreather Mask)

PROCEDURE

Control: Room Air or Low concentration Oxygen

FiO2 \<30% Oxygen (Delivered with 0-2L/min Nasal Cannula)

Sponsors & Collaborators

  • Chinese University of Hong Kong

    lead OTHER

Principal Investigators

  • David YC Chan, MBBS, FRCS · Chinese University of Hong Kong

  • Wai S Poon, MBChB, FRCS · Chinese University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-26
Primary Completion
2023-12-31
Completion
2024-12-31

Countries

  • Hong Kong

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04725851 on ClinicalTrials.gov