Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Summary

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

Conditions

• Multiple System Atrophy
• Parkinson Disease
• Progressive Supranuclear Palsy
• Motor Neuron Disease
• Neurodegenerative Diseases

Sponsors & Collaborators

• University Hospital Muenster

  collaborator OTHER

• Medical University of Warsaw

  collaborator OTHER

• Hannover Medical School

  collaborator OTHER

• University of Ulm

  collaborator OTHER

• Medical University Innsbruck

  collaborator OTHER

• University Hospital Carl Gustav Carus

  collaborator OTHER

• University of Barcelona

  collaborator OTHER

• Seoul National University Hospital

  collaborator OTHER

• Gifu University Graduate School of Medicine

  collaborator OTHER

• University of Bologna

  collaborator OTHER

• Tel Aviv University

  collaborator OTHER

• Asklepios Kliniken Hamburg GmbH

  collaborator OTHER

• Asklepios Fachklinikum Stadtroda

  collaborator OTHER

• Klinikum Osnabrück

  collaborator UNKNOWN

• Kliniken Beelitz GmbH

  lead OTHER

Principal Investigators

• Florin Gandor, MD · Movement Disorders Hospital Beelitz-Heilstätten, Germany

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-09-01

Primary Completion

2027-12-31

Completion

2028-07-31

Countries

• Austria
• Germany
• Israel
• Italy
• Japan
• Poland
• South Korea
• Spain

Study Locations