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Exogenous Ketones for Acutely Decompensated HEart Failure

NCT04698005 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2021-01-06

No results posted yet for this study

Summary

This study will evaluate whether supplementation of exogenous ketones in patients with severe left ventricular dysfunction and acutely decompensated heart failure requiring inotropic therapy would improve the patient's hemodynamics and symptoms.

Conditions

  • Acute Heart Failure
  • Low Cardiac Output Syndrome
  • Hemodynamic Instability
  • Ketosis

Interventions

DIETARY_SUPPLEMENT

25g Ketone monoester without added salts

oral supplementation of ketone monoester

OTHER

Placebo

The patients will receive a placebo drink (drinking water) of equivalent volume (3x 65ml)

Sponsors & Collaborators

  • Institute for Clinical and Experimental Medicine

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-02
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04698005 on ClinicalTrials.gov