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Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging

NCT04680689 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-02-14

No results posted yet for this study

Summary

The aim of the Fused-Heart study is to investigate the impact of a coronary artery stenosis on myocardial function and viability, based on advanced fusion imaging techniques derived from CCTA.

Moreover the study will investigate the correlation between morphology and composition of atheromatous plaques located in a coronary artery and myocardial ischemia in the territory irrigated by the same coronary artery.

Conditions

  • Myocardial Ischemia
  • Myocardial Viability
  • Coronary Stenosis
  • Vulnerable Coronary Plaques

Interventions

DIAGNOSTIC_TEST

128 Multislice CT coronary angiography

128 Multislice CT coronary angiography with the evaluation of coronary stenosis, the plaque vulnerability markers ( necrotic core, low attenuation plaque, spotty calcifications, napkin ring sign, positive remodeling), asses polar maps of the myocardium

DIAGNOSTIC_TEST

2D Cardiac Transthoracic Echocardiography

2D Cardiac Transthoracic Echocardiography with the evaluation of the cardiac cavity dimensions

DIAGNOSTIC_TEST

Laboratory Blood tests

Laboratory tests for evaluations the level of inflammatory biomarkers ( hs-CRP, MMP, IL6 and NT-pro-BNP), complete blood count, biochemestry

Sponsors & Collaborators

  • George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures

    collaborator OTHER

  • Tîrgu Mureș Emergency Clinical County Hospital, Romania

    collaborator OTHER

  • Cardio Med Medical Center

    lead INDUSTRY

Principal Investigators

  • Alexandra Gorea Stanescu, MD · Cardio Med

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-30
Primary Completion
2022-12-01
Completion
2023-01-01

Countries

  • Romania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04680689 on ClinicalTrials.gov