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Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO)

NCT04660448 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 650

Last updated 2022-04-12

No results posted yet for this study

Summary

Bedside lung ultrasonography helps to obtain reliable clinical information about lung aeration, that has been categorized by means of the so-called lung ultrasound score (LUS). In critically ill adults, LUS has been related with the outcome both in patients with respiratory and some non-respiratory conditions. Pediatric studies about lung aeration have been done mainly on postoperative cardiac patients and infants with bronchiolitis. In this prospective, observational, multicenter, feasibility and diagnostic accuracy study, we will explore the degree of lung aeration impairment as a potential outcome predictor in critically ill children with a variety of underlying conditions. Children from 1 month to 18 years of age admitted to PICU will be recruited and LUS will be calculated at two time points: at 12 ± 6 hours and at 48-72 hours. Univariate and multivariate statistical analysis will be performed in order to ascertain the outcome influence of clinical factors in general and LUS in particular.

Conditions

  • Lung Injury
  • Extravascular Lung Water
  • Pulmonary Edema
  • Acute Respiratory Distress Syndrome
  • Shock

Interventions

DIAGNOSTIC_TEST

Bedside lung ultrasound examination

Lung ultrasound exploring 12 areas (6 in each lung) at 12 +/- 6 hours and at 48-72 hours from PICU admission. Clinical and analytical data collection coinciding with ultrasound imaging and during follow-up while admitted to PICU.

Sponsors & Collaborators

  • Fundación para la Investigación Biosanitaria del Principado de Asturias

    lead OTHER

Principal Investigators

  • Guillermo M. Albaiceta, MD PhD · HUCA-FINBA. Universidad de Oviedo

  • Juan Mayordomo-Colunga, MD PhD · HUCA-FIBA

Eligibility

Min Age
1 Month
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2021-03-31
Completion
2021-11-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04660448 on ClinicalTrials.gov