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Surviving the Pediatric Intensive Care Unit (PICU)

NCT06812130 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 404

Last updated 2026-05-05

No results posted yet for this study

Summary

Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient/survivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disruptions in their daily routines, all of which can contribute to long-term negative outcomes if unaddressed. Thus, this study consists of two cohorts to understand the long-term physical, cognitive, and psychological outcomes in PICU survivors and their families, and the short-term impacts on siblings of critically ill children.

Conditions

  • Post Intensive Care Syndrome (PICS)

Interventions

OTHER

This is a non-interventional study.

This is a non-interventional study.

Sponsors & Collaborators

  • National University Hospital, Singapore

    collaborator OTHER

  • Duke-NUS Graduate Medical School

    collaborator OTHER

  • Singapore Clinical Research Institute

    collaborator OTHER

  • KK Women's and Children's Hospital

    lead OTHER_GOV

Principal Investigators

  • A/Prof Lee Jan Hau, MBBS, MRCPCH, MCI · KK Women's and Children's Hospital

Eligibility

Min Age
28 Days
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-11
Primary Completion
2027-06-30
Completion
2027-12-31

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06812130 on ClinicalTrials.gov