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Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso

NCT04650815 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 608

Last updated 2026-03-30

No results posted yet for this study

Summary

Background:

Malaria is a disease that affects many people in Burkina Faso. It is caused by germs that are spread by mosquito bites. A vaccine that blocks the spread of malaria is important to get rid of the disease. To see if a vaccine works, researchers need to find out how many malaria infections are happening in the community.

Objective:

To learn how often people of all ages who live in Sabou, Burkina Faso, get malaria.

Eligibility:

Healthy people ages 6 months to 65 years who reside in Sabou in a household with adults and children.

Design:

Participants will be screened with questions about their health. They will have a physical exam.

Participants will be asked about any malaria symptoms they are having. They will be asked about the use of bed nets. Their vital signs, like blood pressure and temperature, will be measured.

They will have blood taken from their arm with a needle.

Participants who have a fever will have a malaria test. Those who test positive for malaria will be referred to the local health facility for treatment.

Participants will have monthly study visits. Blood will be taken from a finger.

Participants may be invited to take part in 2 mosquito feeding experiments. Mosquitos that do not carry malaria will bite their arm. And a small amount of blood will be fed to mosquitos in a laboratory.

Participants' homes will be examined for mosquitoes. Researchers will remove all mosquitoes they collect. Participants' homes will be sprayed with a chemical to kill mosquitoes and other insects.

Participation will last for 12 months.

Conditions

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    lead NIH

Principal Investigators

  • Patrick E Duffy, M.D. · National Institute of Allergy and Infectious Diseases (NIAID)

Eligibility

Min Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-10
Primary Completion
2024-06-25
Completion
2024-06-25

Countries

  • Burkina Faso

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04650815 on ClinicalTrials.gov