MedTrace Logo

Influence of the Consumption of Conventional and Electric Cigarettes on Skin Circulation

NCT04645914 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 198

Last updated 2020-11-27

No results posted yet for this study

Summary

The survey participants are divided into a smoking and non-smoking group. The smoker group is further divided according to the quantity and quality of nicotine ("normal" smoking, vaping). After reaching a steady state, the cutaneous blood flow at rest in the extremities of all participants is determined by Laser Doppler Imaging as a reference value. Laser Doppler Imaging produces images of the blood flow using perfusion units (PU). Subsequently, the perfusion is measured again after smoking/vaping. The difference in skin perfusion of the extremities is calculated (δ-Perfusion). All measurements are performed under controlled vital parameters (body temperature, systolic and diastolic blood pressure, heart rate) and controlled room temperature as well as 15-minute acclimatization of the patients.

Conditions

  • Nicotine Dependence
  • Vaping
  • Smoking

Interventions

BEHAVIORAL

Use of nicotine product (smoking/vaping)

The smokers/vapers are consuming during the study one nicotine product of their own. The dose is the same as each individual is consuming regularly

Sponsors & Collaborators

  • University Hospital Muenster

    lead OTHER

Principal Investigators

  • Andreas Kyriakou, MD · University Hospital Muenster

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-07-02
Primary Completion
2022-05-30
Completion
2022-12-01

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04645914 on ClinicalTrials.gov