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Effect of Switching From Cigarette Smoking to IQOS on Exercise Capacity

NCT03887117 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 94

Last updated 2021-12-27

Study results available
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Summary

This exploratory study is part of the global clinical assessment program of IQOS. It was designed to provide scientific evidence to further substantiate the reduced risk potential of using a heated tobacco product (the Tobacco Heating System \[THS\] marketed as IQOS) as compared to smoking cigarettes. The main goals of this exploratory study were to assess whether switching from cigarette smoking to using IQOS would influence 1) maximum oxygen uptake during incremental exercise (VO2max) and exercise capacity, 2) ability to perform exercise training and thereby influence 3) VO2max after 12 weeks of exercise training, 4) physiological parameters and biological health markers, and finally 5) physical activity levels in daily life.

Conditions

  • Smoking
  • Exercise Capacity

Interventions

OTHER

IQOS + Exercise Training Program

Switch to IQOS use + participation in a training program

OTHER

IQOS without Exercise Training Program

Switch to IQOS use only, without participation in a training program

OTHER

Cigarette Smoking + Exercise Training Program

Continue to smoke cigarettes + participation in a training program

OTHER

Smoking Abstinence + Exercise Training Program

Switch to smoking abstinence + participation in a training program

Sponsors & Collaborators

  • Philip Morris Products S.A.

    lead INDUSTRY

Principal Investigators

  • Armin Schultz, MD · CRS Clinical Research Services Mannheim GmbH

  • Christelle Haziza, PhD · Philip Morris Products S.A.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2019-11-25
Completion
2020-03-16

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03887117 on ClinicalTrials.gov