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sFlt- 1, PIGF, and Niacin Levels in Women With Premature Ovarian Insufficiency

NCT04641624 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2021-08-31

No results posted yet for this study

Summary

Aim: To evaluate serum soluble fms-like tyrosine kinase-1, proangiogenic protein placental growth factor, and niacin levels in women with premature ovarian insufficiency (POI) and to compare the results with those of healthy subjects.

Methods: This prospective study will be included 45 women with idiopathic premature ovarian insufficiency and 45 controls. The blood for analysis will be obtained at the early follicular phase of the menstrual cycle and serum soluble fms-like tyrosine kinase-1, proangiogenic protein placental growth factor, and niacin levels will be measured using a commercially available ELISA kit.

Conditions

  • Premature Ovarian Insufficiency

Interventions

OTHER

ultrasound assessment

soluble fms-like tyrosine kinase-1, proangiogenic protein placental growth factor, and niacin measurementswith a commercially available enzyme-linked immunosorbent assay (ELISA) kit.

Sponsors & Collaborators

  • Cengiz Gokcek Women's and Children's Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
39 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-20
Primary Completion
2021-06-30
Completion
2021-08-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04641624 on ClinicalTrials.gov