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Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia

NCT06463990 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 302

Last updated 2024-09-03

No results posted yet for this study

Summary

Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.

The triglyceride level and other lipids increase slightly during pregnancy. This increase has a positive effect on the development of the fetus. However, an excessive increase in lipid levels can cause some metabolic disorders such as gestational diabetes and increase feto-maternal morbidity/mortality.

While some existing studies have shown that elevated triglyceride levels can cause fetal macrosomia, others have found no correlation between these two variables. The ratio of triglycerides to HDL is a widely used marker for lipid disorders. In addition, the triglyceride-glucose index is also an index used to detect insulin resistance.

Conditions

  • Fetal Macrosomatia
  • Lipid Metabolism Disorders
  • Hyperlipidemias

Interventions

OTHER

TyG index

association between TyG index and triglyceride to high-density lipoprotein cholesterol ratio with fetal macrosomia

Sponsors & Collaborators

  • Ankara Etlik City Hospital

    lead OTHER_GOV

Principal Investigators

  • Yaprak Engin-Ustun, Prof · Etlik Zubeyde Hanim Women's Health Education and Research Hospital

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2024-07-30
Completion
2024-08-25

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06463990 on ClinicalTrials.gov