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Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio

NCT04640467 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2021-01-13

No results posted yet for this study

Summary

To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress in low-risk pregnancies

Conditions

  • Fetal Growth Retardation
  • Stillbirth
  • Neonatal Respiratory Failure
  • Neonatal Death

Interventions

DIAGNOSTIC_TEST

Biophsical profile

There are five components measured during the biophysical examination. A score of 2 points is given for each component that meets criteria. The test is continued until all criteria are met or 30 minutes have elapsed. The points are then added for a possible maximum score of 10. A total score of 10 out of 10 or 8 out of 10 with normal fluid is considered normal. A score of 6 is considered equivocal, and a score of 4 or less is abnormal.

DIAGNOSTIC_TEST

Cerebroplacental ratio

CPR is the ratio of the Middle Cerebral Artery Pulsatility Index (MCA PI) to the Umbilical Artery Pulsatility Index (UA PI). The pulsatility indices will be measured from an automated trace of at least three consecutive waveforms of the relevant vessel in the absence of fetal breathing movements or uterine contractions. The angle of insonation will be as close to zero degrees as possible. The UA PI will be recorded from a free-floating section of cord, and the MCA PI will be obtained from the proximal third of the vessel (10, 14).

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Mariam Sobhy, MBBCH · Assiut University

  • Ahmed Aboelhasan, MD · Assiut University

  • Moustafa Gadalla, MD · Assiut University

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2022-10-01
Completion
2022-11-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04640467 on ClinicalTrials.gov