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Aerosolized Colistin to Mechanical Ventilated Patients With Pneumonia

NCT04633317 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2023-06-02

No results posted yet for this study

Summary

The purpose of this study was to determine the effect of aerosolized colistin on to ventilated patients with carbapenem-resistant gram negative bacteria pneumonia. We hypothesize that adjunct aerosolized colistin, which achieve high drug concentrations in the airway, would more effectively treat the penumbra.

Conditions

  • Pneumonia, Bacterial

Interventions

DEVICE

A pneumatic nebulizer

Inhaled colistimethate sodium generated by a pneumatic nebulizer

DEVICE

A vibrating mesh nebulizer

Inhaled colistimethate sodium generated by a vibrating mesh nebulizer

Sponsors & Collaborators

  • Chang Gung Memorial Hospital

    collaborator OTHER

  • Chang Gung University

    lead OTHER

Principal Investigators

  • Hui-Ling Lin, MS · Chang Gung University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-15
Primary Completion
2022-07-31
Completion
2022-07-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04633317 on ClinicalTrials.gov