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Different Oral Colonization of Gram-negative Bacteria in ICU Patients When Using Chlorhexidine at 0.12% Versus Chlorhexidine at 2.0%

NCT03442023 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2019-03-11

No results posted yet for this study

Summary

This study will assess the utility of different chlorhexidine mouthwash concentrations on ICU patients to decolonize their oral cavities from gram-negative bacteria, since this is a non-desirable condition that leads to higher mortality rates and longer hospitalization times. One group will receive the 0.12% chlorhexidine mouthwash and the other group will receive the 2% chlorhexidine mouthwash.

Conditions

  • Chlorhexidine
  • Ventilator Associated Pneumonia

Interventions

DRUG

Chlorhexidine gluconate at 2%

Mouth Rinse with Chlorhexidine gluconate at 2% every 12 hours, one week.

DRUG

Chlorhexidine gluconate at 0.12%

Mouth Rinse with Chlorhexidine gluconate at 0.12% every 12 hours, one week.

Sponsors & Collaborators

  • Universidad de Guanajuato

    lead OTHER

Principal Investigators

  • Jose A Alvarez, PhD · Universidad de Guanajuato

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2019-11-30
Completion
2019-12-31

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03442023 on ClinicalTrials.gov