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Baseline Vitamin D Deficiency and COVID-19 Disease Severity

NCT04628000 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2022-10-04

No results posted yet for this study

Summary

It is known that vitamin D has been found to decrease incidence of viral respiratory infections, as well as have effects on multiple cytokines involved in immunomodulation and the bradykinin/renin-angiotensin system.

Recently, data was released showing a correlation between baseline vitamin D deficiency status and increased risk of contracting COVID-19.

Separate analysis shows that many of the deleterious effects of COVID-19 may be due to the bradykinin/RAS system, and that vitamin D is one plausible treatment option to modulate these effects.

Studies are currently ongoing to determine if vitamin D supplementation of those hospitalized with COVID-19 has a beneficial effect on patient outcomes.

Healthcare resources have been strained during the pandemic in areas of heavy caseload. It is possible that those with concurrent vitamin D deficiency and COVID positivity have an increased need for escalation of care. A small study has been conducted in this area, but was limited by small number of subjects.

Conditions

  • Vitamin D Deficiency
  • Covid19

Interventions

OTHER

Vitamin D

Clinical Correlation

Sponsors & Collaborators

  • Parkview Medical Center

    lead OTHER

Principal Investigators

  • Stephanie Lucas, MD · Parkview Medical Center

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-27
Primary Completion
2021-10-14
Completion
2022-04-14

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04628000 on ClinicalTrials.gov