MedTrace Logo

Concomitant Renal and Urinary Bladder Allograft Transplantation

NCT04626167 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-04-23

No results posted yet for this study

Summary

The purpose of this study is to establish if concomitant renal and vascularized urinary bladder allograft transplantation is feasible.

Conditions

  • Chronic Kidney Diseases
  • Bladder Dysfunction
  • Bladder Absence
  • Posterior Urethral Valve
  • Neurogenic Bladder
  • Bladder Exstrophy
  • Bladder Outlet Obstruction
  • Failure, Kidney
  • Transplant

Interventions

PROCEDURE

Concomitant Renal and Urinary Bladder Allograft Transplantation

This is a single-center, prospective, single-group unblinded phase I study that will enroll subjects with chronic kidney disease secondary to bladder dysfunction or bladder absence that is refractory to medical treatment and requires surgical intervention to prevent long-term sequelae. Patients will undergo a cadaveric donor bladder transplant in addition to or after their kidney transplant rather than using intestinal segments for bladder reconstruction or contruction.

Sponsors & Collaborators

Principal Investigators

  • Patricio Gargollo, MD · Mayo Clinic

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
1 Year
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-01
Primary Completion
2026-08-31
Completion
2026-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04626167 on ClinicalTrials.gov