MedTrace Logo

Obstructive Sleep Apnea Destabilizes Myocardial Repolarization Homogeneity

NCT04621032 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 187

Last updated 2020-11-27

No results posted yet for this study

Summary

Literature shows that patients with obesity and Obstructive Sleep Apnea (OSA), both occurring independently, are more likely to develop cardiovascular diseases and sudden cardiac death (SCD). Assuming that ventricular depolarization is more stable than repolarization then QT interval parameters may be used for heart muscle repolarization assessment for those groups of patients.

There were 121 patients included in the study, both - women and men, aging from 35-65 with visceral obesity. Only healthy patients were included - the ones who were not treated for any chronic disease, taking QT elongating drugs, or were not treated with Continuous Positive Airway Pressure (CPAP) therapy at that time.

Conditions

Interventions

DIAGNOSTIC_TEST

Polygraphy monitoring

All patients with visceral obesity have been tested for Obstructive Sleep Apnea and heart rhythm disorders by usage of polygraphy and Holter-ECG monitoring.

DIAGNOSTIC_TEST

laboratory tests

Blood samples for sodium, potassium, calcium, magnesium concentration and fasting glyceamia assessment hae been taken from all patients with visceral obesity.

Sponsors & Collaborators

  • Medical University of Warsaw

    collaborator OTHER

  • Nowodworskie Centrum Medyczne

    lead OTHER

Principal Investigators

  • Aleksandra Jarecka-Dobroń, PhD · NowodworskieMD

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-01
Primary Completion
2019-08-31
Completion
2019-08-31

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04621032 on ClinicalTrials.gov