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Biomarkers for Initiating Onsite and Faster Ambulance Stroke Therapies

NCT04612218 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 176

Last updated 2021-08-26

No results posted yet for this study

Summary

Stroke is the first cause of death among Spanish women and main cause of disability. Reperfusion therapies of the occluded artery remain the only useful approach in acute ischemic stroke. However, the efficacy of these strategies is highly time-dependent and due to the need of neuroimaging (CT or MRI) to differentiate between ischemic and hemorrhagic stroke, impossible to be performed at the pre-hospital level. The investigators aim to set-up a point of-care (POC) device to validate a biomarker panel differentiating ischemic and hemorrhagic stroke at the pre-hospital level using a blood sample and to validate a second biomarker panel for the early identification of patients with large vessel occlusions (LVO), which are candidates for mechanical thrombectomy. For that, the investigators will recruit a 300 patients' cohort with pre-hospital blood samples using available POCs for each of those markers.

Conditions

Sponsors & Collaborators

  • Hospitales Universitarios Virgen del Rocío

    collaborator OTHER

  • Hospital Alta Resolución Sierra Norte

    collaborator UNKNOWN

  • Hospital San Juan de Dios Aljarafe

    collaborator UNKNOWN

  • Hospital Universitario Reina Sofia de Cordoba

    collaborator OTHER_GOV

  • Hospital Universitario Virgen Macarena

    lead OTHER

Principal Investigators

  • Joan Montaner, PhD · Hospital Universitario Virgen Macarena

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-08
Primary Completion
2021-07-28
Completion
2021-07-28

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04612218 on ClinicalTrials.gov