Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry Patients
NCT04577170 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45
Last updated 2023-11-09
Summary
We hypothesize that Fabry disease - FD is associated with elevated vascular resistance induced by cerebral small-vessel disease, indicating increased distal resistance to blood flow. The findings of this study may be used as a precursor for neuroimaging manifestations related to stroke in FD patients.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography
Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography will be performed in consecutive FD patients. All TCD and TCCD studies will be performed by stroke neurologists experienced in vascular sonography.
Sponsors & Collaborators
-
National and Kapodistrian University of Athens
lead OTHER
Eligibility
- Min Age
- 16 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-11-20
- Primary Completion
- 2022-07-01
- Completion
- 2023-01-20
Countries
- Greece
Study Locations
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