Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry Patients

NCT04577170 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2023-11-09

No results posted yet for this study

Summary

We hypothesize that Fabry disease - FD is associated with elevated vascular resistance induced by cerebral small-vessel disease, indicating increased distal resistance to blood flow. The findings of this study may be used as a precursor for neuroimaging manifestations related to stroke in FD patients.

Conditions

Interventions

DIAGNOSTIC_TEST

Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography

Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography will be performed in consecutive FD patients. All TCD and TCCD studies will be performed by stroke neurologists experienced in vascular sonography.

Sponsors & Collaborators

  • National and Kapodistrian University of Athens

    lead OTHER

Eligibility

Min Age
16 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-20
Primary Completion
2022-07-01
Completion
2023-01-20

Countries

  • Greece

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04577170 on ClinicalTrials.gov