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Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions

NCT01208584 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22

Last updated 2015-03-11

No results posted yet for this study

Summary

The purpose of this study is to use functional MRI (fMRI) and magnetic resonance (MR) diffusion tensor imaging (DTI) to investigate brain activation and white matter changes in patients with congenital (birth defect of the spinal column), acute and chronic complete spinal cord lesions. The findings of this study may provide a basis to better understand the pathomechanisms underlying the dynamic neurofunctional changes following a spinal cord lesions in man. This understanding is important for the improvement of existing therapies and for the development of new therapeutic approaches.

Conditions

  • Paraplegia, Spinal
  • Myelomeningocele

Interventions

OTHER

fMRI, DTI

functional magnetic resonance imaging (fMRI), MR diffusion tensor imaging (DTI)

Sponsors & Collaborators

  • Heidelberg University

    collaborator OTHER

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Christoph Stippich, Prof · University Hospital, Basle - Department of Neuroradiology

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2013-10-31
Completion
2013-10-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01208584 on ClinicalTrials.gov