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PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients

NCT02130271 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2019-09-16

No results posted yet for this study

Summary

The purpose of this study is to see if the spine shows areas of inflammation using a specific type of imaging (pictures).

Conditions

  • Sciatica

Interventions

DRUG

Radioactive dye

The radioactive dye \[11C\]PBR28 will be administered through an intravenous line (IV).

RADIATION

PET/MRI

All subjects will undergo a simultaneous PET/MRI scan. The scan will be up to 2 hours long.

OTHER

Blood draw

Up to 11 tablespoons of blood will be drawn through an intravenous line (IV-line) for two purposes: 1) testing for the subject's genetic affinity to the radioactive dye, and 2) testing for the presence inflammatory biomarkers.

Sponsors & Collaborators

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Yi Zhang, MD, PhD. · Massachusetts General Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2016-12-31
Completion
2018-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02130271 on ClinicalTrials.gov