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The Role of Hepcidin as a Biomarker to Predict Successful Renal Transplantation

NCT04575077 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2020-10-05

No results posted yet for this study

Summary

High hepcidin concentrations indicate that iron is blocked from secretion from the reservoir. Hepcidin may be useful in prediction functional iron utilization in renal failure patients. Hepcidin is also associated with chronic renal failure and residual renal function in dialysis patients. Recent studies have shown that hepcidin is a potential marker of impaired renal function in a rat model of chronic nephropathy.

The purpose of this study was to investigate the relationship between preoperative hepcidin levels and the incidence of success rate of kidney transplantation in patients with end-stage renal failure undergoing kidney transplantation surgery. The study is a prospective single-group observational study that analyzes hepcidin as a biomarker.

Conditions

  • End-stage Renal Disease

Sponsors & Collaborators

  • Yonsei University

    lead OTHER

Principal Investigators

  • Bon-Nyeo Koo, PhD · Severance Hospital

Eligibility

Min Age
19 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-16
Primary Completion
2022-02-28
Completion
2022-08-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04575077 on ClinicalTrials.gov