Implementation of an Evidence Based Post-Traumatic Stress Disorder (PTSD) Treatment in Public Sector Settings

Summary

Researchers hope to learn whether a flexibly applied cognitive behavioral treatment for Post-Traumatic Stress Disorder (PTSD) is more effective than the psychotherapy usually provided in the clinic (called Treatment as Usual or TAU). Primary Hypothesis: STAIR/NT will be superior to TAU in improving PTSD symptoms at 28, 36 and 48 weeks post-randomization

Conditions

• Post-Traumatic Stress Disorder

Interventions

BEHAVIORAL

STAIR/NT treatment

STAIR/NT is a two module, sequential treatment in which the first module emphasizes present-focused skills training in affective an interpersonal regulation (STAIR) for day-to-day life difficulties and the second module incorporates past-focused work on the processing of the trauma, using narrative therapy (NT). STAIR/NT is a cognitive behavioral treatment that can be flexibly applied allowing treatment tailored to the needs of the individual patient; may be as brief as 16 sessions and as long as 24.

BEHAVIORAL

Treatment as Usual (TAU)

The Treatment as Usual intervention content varies from site to site and involve some combination of psychotherapy and pharmacotherapy. Treatment duration varies across sites and ranges from 30 to 45 sessions.

Sponsors & Collaborators

• New York University

  collaborator OTHER

• Grady Health System

  collaborator OTHER

• Nathan Kline Institute for Psychiatric Research

  collaborator OTHER

• Georgetown University

  collaborator OTHER

• Harvard Medical School (HMS and HSDM)

  collaborator OTHER

• UConn Health

  collaborator OTHER

• VA New York Harbor Healthcare System

  collaborator FED

• National Institute of Mental Health (NIMH)

  collaborator NIH

• Palo Alto Veterans Institute for Research

  lead OTHER

Principal Investigators

• Marylene Cloitre, PhD · VA Palo Alto Health Care System

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-01-01

Primary Completion

2016-04-01

Completion

2017-04-01

Countries

• United States

Study Locations