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Autism, Emotional Processing, and the Amygdala

NCT04549506 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 51

Last updated 2020-09-16

No results posted yet for this study

Summary

Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy. Considering that inconsistent amygdala reactivity to emotional faces might be ascribed to aberrant attention in ASD, the investigators hypothesized to investigate if there would be an imbalance between conscious and nonconscious emotional processing. This fMRI study recruited 26 youths and young adults with autism spectrum disorder and 25 matched controls, and measured their amygdala reactivity and functional connectivity in response to conscious and nonconscious (backward masked) perception of threatening faces.

Keywords: Autism Spectrum Disorder; amygdala reactivity; emotional processing; fMRI

Conditions

Sponsors & Collaborators

  • Yawei Cheng

    lead OTHER

Eligibility

Min Age
13 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-19
Primary Completion
2016-09-21
Completion
2017-06-16

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04549506 on ClinicalTrials.gov