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The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis (EFEX-OA-01)

NCT04542655 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2021-02-15

No results posted yet for this study

Summary

Aim of EFEX-OA-01: To explore how running, cycling and resting acutely influence levels of collagen and proteoglycan in patients with osteoarthritis knee and in young healthy subjects, as reflected by changes in serum and urine biochemical markers originating from joint related collagens and proteoglycans.

Conditions

  • Osteoarthritis, Knee

Interventions

OTHER

Ergometer Cycling followed by treadmill running

The participants undergo ergometer cycling, treadmill running and rest.

OTHER

Treadmill Running followed by ergometer cycling

The participants undergo treadmill running, ergometer cycling and rest.

OTHER

Rest

The participants undergo ergometer cycling, treadmill running and rest.

Sponsors & Collaborators

  • University of Copenhagen

    collaborator OTHER

  • NBCD A/S

    collaborator INDUSTRY

  • Nordic Bioscience A/S

    lead INDUSTRY

Principal Investigators

  • Henning Nielsen, MD, DMSci · Sanos Clinic

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-07
Primary Completion
2019-05-14
Completion
2019-05-14

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04542655 on ClinicalTrials.gov