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Astaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory Indicators

NCT03664466 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2022-04-19

No results posted yet for this study

Summary

This study is intended to assess the effects of astaxanthin use on pain, physical function, and inflammation as reflected by Patient-Reported Outcomes Measurement Information System (PROMIS) scores and levels of inflammatory biomarkers in subjects taking astaxanthin. If improvements in pain, function, and/or markers of inflammation could be demonstrated with the use of astaxanthin, this may suggest the potential for astaxanthin to be used in management of knee osteoarthritis (and possibly other forms of osteoarthritis) with less evident toxicity than seen with the presently available standard therapies (e.g. NSAIDS, opioids).

Conditions

  • Osteoarthritis, Knee

Interventions

DIETARY_SUPPLEMENT

astaxanthin

astaxanthin capsules 12 mg twice daily

OTHER

Placebo

placebo capsules twice daily

Sponsors & Collaborators

  • Saint Luke's Health System

    lead OTHER

Principal Investigators

  • Jennifer Elliott, MD · St. Luke's Hospital, Kansas City, Missouri

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-29
Primary Completion
2022-01-25
Completion
2022-01-25

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03664466 on ClinicalTrials.gov