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Real Time Evaluation of Dynamic Changes of the Lungs During Respiratory Support of VLBW Neonates Using EIT

NCT04542096 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2025-03-28

No results posted yet for this study

Summary

Electric Impedance Tomography (EIT) is a lung monitoring technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice of the thorax. It is a real time, radiation free, non-invasive and portable. Neonatal respiratory distress syndrome (RDS) is a respiratory disorder resulting from immaturity of the lung structure and lack of surfactant. It is one the most common conditions in premature infants. Many of these infants require either invasive or non-invasive respiratory support. The goal of the study is to investigate the dynamic changes in pulmonary aeration during assisted breathing in very low birthweight preterm infants using pulmonary electrical impedance tomography. Currently most widely used methods to assess respiratory lung function are either invasive and/or indirect (ABG, pulse oximetry, transcutaneous pCO2 measurement), lacks temporal resolution (lung ultrasound) or emit ionizing radiation (CT). EIT provides information on regional lung aeration without the aforementioned shortcomings.

Conditions

  • RDS - Infants
  • RDS of Prematurity
  • Respiratory Failure
  • Prematurity
  • Very Low Birth Weight Infant

Interventions

DEVICE

Lung electrical impedance tomography monitoring

A belt for recording changes in electrical impedance in the skin will be fastened for the purpose of this study with no other additional procedures

Sponsors & Collaborators

  • Vilnius University

    lead OTHER

Principal Investigators

  • Arūnas Liubšys, MD · Vilnius University

Eligibility

Min Age
22 Weeks
Max Age
36 Weeks
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-29
Primary Completion
2024-04-20
Completion
2024-05-20

Countries

  • Lithuania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04542096 on ClinicalTrials.gov