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Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)

NCT04525989 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 254

Last updated 2025-08-20

No results posted yet for this study

Summary

To investigate a potential toxicity benefit of preoperative radiation therapy with protons compared to conventional photon beam radiation therapy in patients with locally advanced rectal cancer.

Conditions

Interventions

RADIATION

Radiation therapy

5 x 5 Gy external radiation therapy

Sponsors & Collaborators

  • Alexander Valdman

    lead OTHER

Principal Investigators

  • Alexander Valdman, MD, PhD · Department of Radiotherapy, Karolinska University Hospital, Stockholm, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-20
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • Sweden

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04525989 on ClinicalTrials.gov