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Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

NCT04523961 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2026-02-20

Study results available
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Summary

The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.

Conditions

  • Anesthesia, Local
  • Photodamaged Skin
  • Topical and Infiltration Anesthetic Toxicity

Interventions

DRUG

2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion

Topical anesthetic used to numb the skin prior to laser procedures

DRUG

7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion

Topical anesthetic used to numb the skin prior to laser procedures

Sponsors & Collaborators

Principal Investigators

  • Elika Hoss · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-08
Primary Completion
2025-02-19
Completion
2025-02-19
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04523961 on ClinicalTrials.gov