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Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena

NCT00798018 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2009-12-18

Study results available
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Summary

It has been proven that tracheal tube inflated with lidocaine could decrease the post-intubation sore throat in nitrous oxide anesthesia. In the study, the investigators would like to evaluate the effect of lidocaine inflation in non-nitrous oxide anesthesia and compare the effect of tetracaine, the best mucosal local anesthetics with lidocaine.

Conditions

  • Pharyngitis

Interventions

DRUG

2% lidocaine

lidocaine: 2%, injected into the cuff to seal the space between the trachea and the tube at minimal volume

DRUG

placebo

Air injected into the cuff to seal the space between the trachea and the tube at minimal volume

DRUG

1% tetracaine

tetracaine: 1%, injected into the cuff to seal the space between the trachea and the tube at minimal volume

DRUG

N.S

0.9% Normal saline injected into the cuff to seal the space between the trachea and the tube at minimal volume

Sponsors & Collaborators

  • Sichuan University

    lead OTHER

Principal Investigators

  • Han Huang, M.D · Department of Aensthesiology, West China 2nd Hospital, Sichuan University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2009-02-28
Completion
2009-02-28

Countries

  • China

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00798018 on ClinicalTrials.gov