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Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression

NCT01433224 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2016-05-18

No results posted yet for this study

Summary

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.

PURPOSE: This research trial studies samples from younger patients with malignant germ cell tumor progression.

Conditions

  • Childhood Germ Cell Tumor
  • Extragonadal Germ Cell Tumor
  • Ovarian Cancer
  • Testicular Germ Cell Tumor

Interventions

GENETIC

DNA methylation analysis

GENETIC

RNA analysis

GENETIC

mutation analysis

GENETIC

nucleic acid sequencing

GENETIC

polymerase chain reaction

GENETIC

polymorphism analysis

OTHER

laboratory biomarker analysis

OTHER

medical chart review

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • James F. Amatruda, MD, PhD · Simmons Cancer Center

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-10-31
Primary Completion
2016-05-31
Completion
2016-05-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01433224 on ClinicalTrials.gov