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Effects of Therapeutic Plasmaexhange on Viscoelastic Tests in Non-coagulopathic Patients

NCT04513249 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2020-08-14

No results posted yet for this study

Summary

Therapeutic plasma exchange is widely performed in patients with autoimmune disease. The exact effects of fresh frozen plasma on coagulation in this group of patients remains unknown. In order to investigate this issue the present study monitors periprocedural coagulation status with the aid of standard coagulation tests and rotational thromboelastometry. Four thromboelastometric tests will be performed: ExTEM, InTEM, FibTEM and ApTEM. The following parameters will be recorded from each test: CT (sec), CFT (sec) and MCF (mm) one hour before and one hour after plasmaechange was performed.

Conditions

  • Transfusion Related Complication

Interventions

DIAGNOSTIC_TEST

dynamics of coagulation parameters

the effects of fresh frozen plasma administered during a plasma exchange therapy on viscoelastic tests

Sponsors & Collaborators

  • Institutul Clinic Fundeni

    lead OTHER

Principal Investigators

  • Dana Tomescu, Prof · Fundeni Clinical Institute

Eligibility

Min Age
18 Minutes
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-05-10
Primary Completion
2017-12-30
Completion
2017-12-30

Countries

  • Romania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04513249 on ClinicalTrials.gov