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Extinction Learning in Adults With Tourette Syndrome

NCT04498364 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2023-10-23

No results posted yet for this study

Summary

Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

Conditions

  • Tourette Syndrome
  • Habit Reversal Training
  • Tic Disorders
  • Tics
  • Comprehensive Behavioral Intervention for Tics

Interventions

BEHAVIORAL

Habit Reversal Training

Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics.

Sponsors & Collaborators

Principal Investigators

  • Joseph F McGuire, PhD · Johns Hopkins University

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-09-18
Primary Completion
2023-09-22
Completion
2023-10-17

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04498364 on ClinicalTrials.gov