MedTrace Logo

Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study

NCT04474743 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 345

Last updated 2021-11-02

No results posted yet for this study

Summary

Malnutrition and muscle wasting are common consequences of life-threatening, chronic diseases of the gastrointestinal tract. Such diseases include liver cirrhosis, chronic pancreatitis and short bowel syndrome. Malnutrition and muscle wasting increase the risk of complications, reduce the life expectancy and impair the quality of life. The development of malnutrition and muscle wasting is different, as is the diagnosis and nutritional treatment. There are also different mechanisms of origin for the underlying diseases. The aim of the study is to compare data related to nutrition and physical condition of patients with liver cirrhosis, chronic pancreatitis and short bowel syndrome. Malnutrition and muscle wasting within the specific diseases will be characterized and possible correlations will be identified.

For this, malnourished and non-malnourished patients of the different diseases are compared with controls patients with non-specific complaints of the gastrointestinal tract as well as with healthy study participants.

Data on food intake, physical activity, body composition and body measurements as well as muscle strength and muscle function are recorded. Blood values as well as transport and barrier properties of the intestine will also be examined.

Conditions

  • Liver Cirrhoses
  • Chronic Pancreatitis
  • Short Bowel Syndrome

Interventions

OTHER

No intervention - cross-sectional observational only

No intervention - cross-sectional observational only

Sponsors & Collaborators

  • University Medical Center Rostock

    collaborator OTHER

  • University of Applied Sciences Neubrandenburg

    collaborator OTHER

  • Leibniz Institute for Farm Animal Biology (FBN)

    collaborator UNKNOWN

  • University Medicine Greifswald

    lead OTHER

Principal Investigators

  • Prof. Dr. med. Lamprecht · University Medicine Rostock

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-02
Primary Completion
2021-09-13
Completion
2021-09-13

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04474743 on ClinicalTrials.gov