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Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia

NCT04456777 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2020-07-02

No results posted yet for this study

Summary

Research goals:

1. Examination of the relationship between the use of vortioxetine and cognitive efficacy in patients with schizophrenia.
2. Examination of the association between the use of vortioxetine and the presence depressive symptoms, physical and social anhedonia in patients with the disease from schizophrenia.
3. Examining the association between vortioxetine use and quality of life

(functional recovery) in patients with schizophrenia

Expected results (hypotheses)

1. Patients with schizophrenia treated with additional therapy vortioxetine will show better cognitive achievement in memory (short-term and long-term), attention, logical reasoning and reasoning, speed of information processing, processing of visual and sound information, language and speech in relation to patients without additional intervention.
2. Patients with schizophrenia treated with additional therapy vortioxetine will have a less pronounced presence of depressive symptoms, physical and social anhedonia in relation to untreated patients with additional vortioxetine therapy.
3. Patients with schizophrenia who were treated with additional therapy vortioxetine will have a better quality of life, ie. better functional recovery

Conditions

  • Cognitive Deficit

Interventions

DRUG

Vortioxetine

vortioxetine will be administreted for 3 months

Sponsors & Collaborators

  • Alen Greš

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2022-07-01
Completion
2022-07-01

Countries

  • Croatia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04456777 on ClinicalTrials.gov