γδT Cell Infusion to Prevent Relapsed/Refractory Leukemia Rescue Relapse
NCT04439721 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2021-01-06
Summary
Safety and Effectiveness of Donor γδT Cell Infusion to Prevent Relapsed/Refractory Leukemia Rescue Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Conditions
- Leukemia, B-cell
Interventions
- DRUG
-
γδT Cell infusion agent
γδT
Sponsors & Collaborators
-
The First Affiliated Hospital of Soochow University
collaborator OTHER -
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Suning Chen, Ph.D · Hematology,The First Affiliaated Hospital Of Soochow University
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 10 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-05-01
- Primary Completion
- 2021-05-01
- Completion
- 2021-05-01
Countries
- China
Study Locations
More Related Trials
-
Infusion of Genetically Modified T Cell for Post Transplant Patients With Relapsed Disease
NCT00871702 ·Status: COMPLETED ·Phase: PHASE1
-
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
NCT00569283 ·Status: COMPLETED ·Phase: PHASE1
-
Risk-adapted Donor Lymphocyte Infusion After Allo-HSCT in Children With Hematologic Malignancy
NCT05009719 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
New Therapy for Advanced Stage Leukemia After Stem Cell Transplantation
NCT01455272 ·Status: COMPLETED ·Phase: NA
-
Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation
NCT06529731 ·Status: RECRUITING ·Phase: PHASE2
-
Suicide Gene Therapy for Donor Lymphocytes Infusion After Allogeneic Hematopoietic Stem Cell Transplantation
NCT01086735 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS
NCT00025662 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Donor Chose on the Outcomes of GVHD Prophylaxis Underwent the Combined Treatment of ATG/PTCy for Haplo-HSCT
NCT06686173 ·Status: NOT_YET_RECRUITING
-
A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.
NCT04688021 ·Status: UNKNOWN ·Phase: PHASE2
-
Vaccination With GM-K562 Cells in Patients With Advanced Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) After Allogeneic Hematopoetic Stem Cell Transplantation
NCT00809250 ·Status: COMPLETED ·Phase: PHASE1
-
Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant
NCT02684162 ·Status: COMPLETED ·Phase: PHASE2
-
T-Lymphocytes Genetically Targeted to the B-Cell Specific Antigen CD19 in Pediatric and Young Adult Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
NCT01860937 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation
NCT00003887 ·Status: COMPLETED ·Phase: PHASE2
-
Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)
NCT01518153 ·Status: TERMINATED ·Phase: PHASE2
-
GVAX vs. Placebo for MDS/AML After Allo HSCT
NCT01773395 ·Status: TERMINATED ·Phase: PHASE2
-
Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant
NCT00068718 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Preliminary Efficacy of Donor-derived Anti-leukemia Cytotoxic T Lymphocytes for the Prevention of Leukemia Relapse in Children Given Haploidentical Hematopoietic Stem Cell Transplantation
NCT06865352 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Prophylactic Intervention for Relapse Prevention Post-Allogeneic Transplantation in Very High-Risk MDS Patients Based on IPSS-M Stratification
NCT06612944 ·Status: RECRUITING ·Phase: PHASE2
-
Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion
NCT00987987 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Peg Interferon α-2b for Relapsed Hematological Malignancies After Allo-HSCT
NCT02634294 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Reduced Intensity Stem Cell Transplantation for Chronic Lymphocytic Leukemia Followed by Vaccination
NCT00442130 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Donor Lymphocyte Infusion (DLI) and Activated DLI Following Relapse After Allogeneic Stem Cell Transplant
NCT00674427 ·Status: TERMINATED ·Phase: PHASE1
-
Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT
NCT05015426 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Reduced-intensity Conditioning Allogeneic Hematopoietic Cell Transplantation
NCT01252784 ·Status: UNKNOWN
-
Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell Transplantation
NCT00374933 ·Status: COMPLETED ·Phase: PHASE1