Effect of Donor Chose on the Outcomes of GVHD Prophylaxis Underwent the Combined Treatment of ATG/PTCy for Haplo-HSCT
NCT06686173 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 114
Last updated 2025-01-07
Summary
This is a prospective, multicenter, cohort study. The high-risk, relapse and refractory AML patients were enrolled in this study. And the goal of this study is to study the effect of the parous female donor and young male donor on the outcomes of graft-versus-host disease (GVHD) prophylaxis underwent the combination of ATG and PTCy for haploidentical peripheral blood stem cell transplantation
Conditions
- High-Risk Acute Myeloid Leukemia
- Relapse And/or Refractory AML
Interventions
- OTHER
-
None-placebo
This is one kind descriptive study. The different donor groups made the cohorts different: the parous female donor and young male donor
- OTHER
-
non-intervention study
This study is one kind of non intervention study
- OTHER
-
donor selection
the intervention of this study was the different donor groups: the parous female donor and young male donor. All the patients involved in this study were treated by the combination of ATG and PTCy
Sponsors & Collaborators
-
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-01
- Primary Completion
- 2027-02-01
- Completion
- 2028-02-01
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