fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
NCT04439552 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2025-12-19
Summary
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
Conditions
- Pain, Postoperative
- Pain, Chronic
- Pain, Acute
- Surgical Injury
- Surgical Wound
- Cornea Injury
- Cornea
- Keratoconus
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Eric A Moulton, OD PhD · Boston Children's Hospital
Eligibility
- Min Age
- 8 Years
- Max Age
- 35 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-10-04
- Primary Completion
- 2027-08-31
- Completion
- 2027-12-31
Countries
- United States
Study Locations
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