The Microbiome of Oesophageal Squamous Cell Carcinoma
NCT04425122 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2023-02-08
Summary
This is a prospective study on the microbiota associated with oesophageal squamous cell carcinoma (SCC). Patients with newly diagnosed SCC of oesophagus would be recruited for taking samples of oral and oesophageal rinse, tissue biopsies for investigation of the microbiota of oesophageal cancer. Control patients would be identified from patients scheduled for routine endoscopy.
Conditions
- Esophageal Cancer
- Microbial Colonization
Interventions
- DIAGNOSTIC_TEST
-
Upper endoscopy
Upper endoscopy would be performed. Biopsy would be taken from oesophageal cancer tissue and adjacent non-cancerous mucosa
- DIAGNOSTIC_TEST
-
Upper endoscopy
Upper endoscopy would be performed. Random biopsy would be taken from normal non-cancer esophageal mucosa.
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Principal Investigators
-
Hon Chi Yip, FRCSEd · Chinese University of Hong Kong
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-07-01
- Primary Completion
- 2023-09-30
- Completion
- 2023-12-31
Countries
- Hong Kong
Study Locations
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