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Histological, Genetic and Epigenetic Analysis of Procedures Related with Dental Implants

NCT04421066 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-02-26

No results posted yet for this study

Summary

In this study genomic, proteomic and histological technologies for the search and characterization of epigenetic modifications and molecular or protein markers, useful in the diagnosis and progression of peri-implant diseases and prevention of implant failure will be used.

Conditions

  • Peri-Implantitis
  • Peri-implant Mucositis
  • Implant Complication
  • Implant Tissue Failure

Interventions

PROCEDURE

Gingival and bone sample collection

Gingival and bone samples will be collected from the sites affected by peri-implantitis during their surgical treatment of peri-implantitis or histological and epigenetic analysis.

PROCEDURE

Healthy individuals

Gingival and bone samples will be collected from the extraction sites for histological and epigenetic analysis.

Sponsors & Collaborators

  • NYU Langone Health

    collaborator OTHER

  • Göteborg University

    collaborator OTHER

  • University Hospital A Coruña

    collaborator OTHER

  • Instituto de Investigacion Biomedica de A Coruna

    collaborator OTHER

  • Simón Pardiñas López

    lead OTHER

Principal Investigators

  • Simón Pardiñas López, DDS, MS · Fundación Clínica Pardiñas

Eligibility

Min Age
20 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-29
Primary Completion
2021-10-21
Completion
2022-06-20

Countries

  • Spain

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04421066 on ClinicalTrials.gov