COVID-19: Herd Immunity Study in the Czech Republic

Summary

The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on direct detection of SARS-CoV- 2, including individuals with a subclinical course of the disease.

Conditions

• COVID
• SARS-CoV 2

Interventions

DIAGNOSTIC_TEST

SARS-CoV-2 diagnostic rapid test

The rapid test detects the presence of antibodies against SARS-CoV-2 in the IgM and IgG class by the immunochromatographic reaction. It cannot detect early infection, the antibodies will probably appear two weeks after possible infection. The collection will be performed by finger puncture.

DIAGNOSTIC_TEST

Quantitative analysis of SARS-CoV-2 antibodies

The subsample from Olomouc region (Olomouc, Uničov, Litovel) is based on venous blood sampling and archiving for subsequent quantitative analysis of SARS-CoV-2 antibodies. These tests detect immunoglobulins M and G (IgM and IgG).

Sponsors & Collaborators

• Ministry of Health, Czech Republic

  collaborator OTHER_GOV

• Palacky University

  collaborator OTHER

• Masaryk University

  collaborator OTHER

• University of Ostrava

  collaborator OTHER

• Faculty of Military Health Sciences, University of Defence in Brno

  collaborator UNKNOWN

• Faculty of Health Studies, J. E. Purkyně University in Ústí nad Labem

  collaborator UNKNOWN

• Charles University, Czech Republic

  collaborator OTHER

• Institute for Clinical and Experimental Medicine

  collaborator OTHER_GOV

• General University Hospital, Prague

  collaborator OTHER

• University Hospital Olomouc

  collaborator OTHER

• Brno University Hospital

  collaborator OTHER

• Krajská zdravotní, a.s., Ústí nad Labem Region Hospitals

  collaborator UNKNOWN

• Military University Hospital, Prague

  collaborator OTHER

• Masaryk Memorial Cancer Institute

  collaborator OTHER

• Czech Academy of Sciences

  collaborator OTHER

• Czech Statistical Office

  collaborator UNKNOWN

• Faculty of Medicine in Hradec Králové, Charles University

  collaborator UNKNOWN

• Institute of Health Information and Statistics of the Czech Republic

  lead OTHER_GOV

Principal Investigators

• Roman Chlíbek, Prof. · University of Defence in Brno

• Rastislav Maďar, Assoc. Prof. · University of Ostrava, Faculy of Medicine

• Marián Hajdúch, Assoc. Prof. · Institute of Molecular and Translational Medicine

• Ladislav Dušek, Prof. · Institute of Health Information and Statistics of the Czech Republic

• Roman Prymula, Prof. · Ministry of Health, Czech Republic

• Jarmila Rážová, M.D.; Ph.D. · Ministry of Health, Czech Republic

• Věra Adámková, Prof. · Institute for Clinical and Experimental Medicine

• Aleksi Šedo, Prof. · Charles University, First Faculty of Medicine

• Vladimír Černý, Prof. · Charles University, Faculty of Medicine in Hradec Králové

• Jaroslav Štěrba, Prof. · Brno University Hospital

• David Feltl, Prof. · General University Hospital, Prague

• Martin Repko, Prof. · Masaryk University, Faculty of Medicine

• Dalibor Valík, Prof. · Masaryk Memorial Cancer Institute

• Zdeněk Havel, Assoc. Prof. · J. E. Purkyně University in Ústí nad Labem, Faculty of Health Studies

Eligibility

Min Age

8 Years

Max Age

89 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-04-23

Primary Completion

2020-05-01

Completion

2020-05-01

Countries

• Czechia

Study Locations