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Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students

NCT05756582 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2040

Last updated 2024-02-13

No results posted yet for this study

Summary

This study is a cross-sectional study that examines the prevalence of Latent Tuberculosis Infection \[LTBI\], defined as individuals infected with Mycobacterium tuberculosis with no clinical evidence of disease, and the possible risk factors of LTBI in a large cohort of health care workers (HCWs) and students.

Conditions

  • Tuberculosis
  • Tuberculosis, Pulmonary
  • Tuberculosis Infection
  • Latent Tuberculosis
  • Health Care Associated Infection

Interventions

DIAGNOSTIC_TEST

Prevalence of Latent Tuberculosis Infection

The prevalence of Latent Tuberculosis Infection \[LTBI\] is defined as 1) tuberculin conversion after a documented negative-baseline tuberculin skin test (TST), 2) positive result of the QuantiFERON-TB Gold (QFT) test performed \[higher response than the cut-off value of 0.35 IU / ml of INF-γ was detected in at least one test tube (TB1 or TB2)\], 3) chest imaging excluding pleural and/or pulmonary lesions suggestive of active tuberculosis and 4) final medical evaluation done by a Specialist in Infectious Diseases which excluded active disease. All four criteria must be met.

Sponsors & Collaborators

  • Eleonora Nucera

    lead OTHER

Principal Investigators

  • Angela Rizzi, MD, PhD · Catholic University of Sacred Heart

  • Eleonora G Nucera, Prof., MD · Catholic University of Sacred Heart

  • Domenico Staiti, Prof., MD · Catholic University of Sacred Heart

  • Antonio Gasbarrini, Prof., MD · Catholic University of Sacred Heart

  • Vincenzo Valentini, Prof., MD · Catholic University of Sacred Heart

Eligibility

Min Age
18 Years
Max Age
72 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-11-17
Primary Completion
2026-06-30
Completion
2026-12-15

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05756582 on ClinicalTrials.gov