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Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)

NCT04388943 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 9500

Last updated 2023-11-29

No results posted yet for this study

Summary

This project will examine the diagnosis and prognosis of patients with cardiovascular disease in hospital in- and outpatients and compare their characteristics with normal controls from the community. The cardiovascular diseases studied include coronary artery disease, heart failure, heart attacks, valve disease, cardiac surgery, dysrhythmias, aneurysms, embolism, strokes, peripheral vascular disease and hypertension. Current methods for diagnosis and predicting outcome in patients are limited and may lack accuracy. This study will collect clinical details, and blood and urine samples from patients for analysis of proteins, chemicals and genetic biomarkers which will enable an examination of the pathological mechanisms involved in cardiovascular disease. The data will also be used to improve diagnosis and also improve prediction of outcome in patients (future clinical events such as death, further hospitalisation with cardiovascular disease and the effects of any therapy given to the patients). In this way, we can develop accurate ways of assessing a patient's condition and how it could be effectively managed. The study will last for 20 years.

Conditions

Interventions

OTHER

Observation

Physiological Measurements Patient reported questionnaire Blood sampling

Sponsors & Collaborators

  • University of Leicester

    collaborator OTHER

  • University Hospitals, Leicester

    lead OTHER

Principal Investigators

  • Nilesh J Samani, Professor · NIHR Leicester Biomedical Research Centre

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-06-17
Primary Completion
2027-03-31
Completion
2027-03-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04388943 on ClinicalTrials.gov