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Impact of Early Cardiac Surgery in Severe Left Endocarditis With Neurological Complications: a Retrospective Study

NCT04387513 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 192

Last updated 2020-05-19

No results posted yet for this study

Summary

Surgical delay in severe endocardits, with neurological complications, is still debated. Early surgery, if indicated, permits to avoid new embolic events, or to fix valvular damages, but can create or increase a cerebral hemorrage.

Hypothesis Cardiac surgery, as soon as possible, if indicated, would reduce mortality, in severe left endocarditis, with neurological complications.

Primary objective To assess the impact of early versus late cardiac surgery on mortality at 1 year, in patients with severe endocarditis, with neurological complications.

Primary endpoint:

1\) Mortality at 1 year

Secondary endpoints:

1. Analyze the factors associated with neurological degradation
2. Evaluate the neurological tolerance of cardiac surgery.

Conditions

  • Endocarditis
  • Neurologic Complication

Interventions

PROCEDURE

Cardiac surgery

Cardiac surgery, if indicated, delayed or not by neurological complications

Sponsors & Collaborators

  • Gros, Alexandre, M.D.

    lead INDIV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-01
Primary Completion
2010-08-18
Completion
2017-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04387513 on ClinicalTrials.gov