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MicroRNA-126 and Its Target VCAM-1Dermatitis to Nickel

NCT04365140 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2020-04-29

No results posted yet for this study

Summary

Background. Allergic Contact Dermatitis (ACD) is an inflammatory skin disease mediated by direct contact with allergens as nickel, the most common allergen, that may be related with epigenetic changes.

Objective. Evaluate the miR-126 expression and its target VCAM-1, in the skin of patients with ACD to nickel.

Methods. Fifteen patients with positive patch test to nickel were included, and the expression of miR-126 and VCAM-1 was evaluated by RT-qPCR.

Conditions

  • Allergic Contact Dermatitis

Sponsors & Collaborators

  • Universidad Autonoma de San Luis Potosí

    lead OTHER

Principal Investigators

  • Juan P Castanedo-Cazares, MD · Dermatology Department. Hospital Central "Dr. Ignacio Morones Prieto"

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2019-11-01
Completion
2019-11-30

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04365140 on ClinicalTrials.gov