Familial and Environmental Factors Behind Migraine
NCT04356079 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80
Last updated 2020-04-22
Summary
Migraine is a chronic neurological disease characterized by recurrent moderate to severe headaches often in association with a number of autonomic nervous system symptoms. Migraines are believed to be due to a mixture of environmental and genetic factors. About two-thirds of cases run in families. Changing hormone levels may also play a role, as migraines affect slightly more boys than girls before puberty, but about two to three times more women than men after puberty. The risk of migraines usually decreases during pregnancy. The exact mechanisms of migraine are not known. It is, however, believed to be a neurovascular disorder. The primary theory is related to increased excitability of the cerebral cortex and abnormal control of pain neurons in the trigeminal nucleus of the brainstem.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
International Headache Society Test
Thorough History of Patients and families
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Min Age
- 15 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-30
- Primary Completion
- 2020-08-31
- Completion
- 2020-08-31
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