MedTrace Logo

Study of the Molecular Genetics of Menstrual Migraine

NCT00904150 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 585

Last updated 2014-02-24

Study results available
· View outcomes & findings →

Summary

The investigators hypothesize that genes that play a role in menstrual migraine can be identified using a well characterised migraine population and a comprehensive genome-wide association scan approach.

The aim of the study is to identify genes, genetic regions, and the effect of hormones on expression profiles in women with menstrual migraine compared to a control population with no personal or first-degree family history of migraine.

In this case control study, saliva samples will be taken from 300 cases and 300 controls for DNA analysis. Blood samples from 30 cases and 30 controls will be taken during the follicular phase as well as the luteal phase of the menstrual cycle for ribonucleic acid (RNA) analysis.

Conditions

Sponsors & Collaborators

  • Griffith University

    collaborator OTHER

  • The City of London Migraine Clinic

    lead OTHER

Principal Investigators

  • E A MacGregor, FFSRH MD · Centre for Neuroscience and Trauma, Queen Mary, University of London

  • Lyn Griffiths, BSc(Hons) PhD · Genomics Research Centre Griffith University

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-11-30
Primary Completion
2013-08-31
Completion
2013-08-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00904150 on ClinicalTrials.gov