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APEMESH- Preventing Perineal Complications After Abdominoperineal Resection

NCT04334421 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2024-02-01

No results posted yet for this study

Summary

Abdominoperineal resection leaves an empty space to be filled by mesh or musculocutaneus flap. Several studies have reported over 30% morbidity with perineal wound healing after abdominoperineal resection. Preoperative radiotherapy is a strong predictor for perineal complications. Musculocutaneus flaps and use of biological mesh seem to minimize perineal morbidity. The role of omentoplasty at APR is controversial.

Previous studies on synthetic mesh repair on perineum are almost lacking.

Conditions

Interventions

DEVICE

Composite mesh

Pelvic floor is reconstructed by synthetic composite mesh (Symbotex, Medtronic) to improve healing and prevent perineal herniation.

Sponsors & Collaborators

  • Elisa Mäkäräinen

    lead OTHER

Principal Investigators

  • Elisa Mäkäräinen-Uhlbäck, M.D. · Oulu University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-04-03
Primary Completion
2021-02-28
Completion
2022-02-28

Countries

  • Finland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04334421 on ClinicalTrials.gov