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Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme

NCT03041532 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 692

Last updated 2020-02-19

No results posted yet for this study

Summary

Colorectal cancer (CRC) is the most common tumor and the second leading cause of death in the Western world. The decrease in incidence and mortality by CRC in the population undergoing screening has been observed. Colonoscopy is the recommended method for detecting tumors in early stages, as well as identifying and resecting adenomatous polyps, which are the precursor lesions of most CRCs. Colonoscopy should be of high quality to decrease incidence and mortality by CRC and avoid interval cancer. The literature shows that colonoscopy does not prevent right colon lesions in the same way as the left colon lesions, with most of the interval cancers located in the right colon. Studies published so far show an increase in the adenomas detection rate (ADT) in the right colon in the second visualization of this segment and an increase between 2 and 10% if this second examination is performed with the proximal retroflexion maneuver.Retroflexion is a safe maneuver in expert endoscopists. The aim of our study is to evaluate the ADT in the right colon by means of a second visualization by performing proximal retroflexion or second frontal visualization at random in the CCR screening population.

Conditions

  • Colorectal Neoplasms
  • Adenoma Detection Rate

Interventions

PROCEDURE

Proximal retroflexion

The investigator explore twice right colon, first front view and second forward viewing or proximal retroflexion depends on randomization

PROCEDURE

Frontal view

The investigator explore twice right colon with frontal viewing

Sponsors & Collaborators

  • Hospital del Rio Hortega

    lead OTHER

Principal Investigators

  • Mª Henar Núñez Rodriguez · Hospital del Rio Hortega Valladolid, Spain

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
69 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2018-10-30
Completion
2018-11-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03041532 on ClinicalTrials.gov