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Cardiac MRI and Cardiac Allograft Rejection

NCT04311346 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2020-03-17

No results posted yet for this study

Summary

In this a prospective, blinded, collaboration study between pediatric and adult transplant departments. Cardiac MRI data on patient with heart transplantations will be collected during years 2020-2022. Based on sample size calculations, the data has enough power to answer the question, whether MRI can be used as a noninvasive diagnostic tool for detection of acute rejection as such or whether it can be used as fist line noninvasive screening tool for detecting those needing for the more detailed invasive study. A clinical protocol will be developed to optimize the management and outcome of the patients having cardiac transplantation aiming to decrease the number of invasive procedures in these patients.

Conditions

  • Rejection Heart Transplant

Interventions

DIAGNOSTIC_TEST

Cardiac MR

Cardiac MR diagnostic tool for detection of acute rejection, double blind comparison with invasive cardiac biopsy

Sponsors & Collaborators

  • Helsinki University Central Hospital

    lead OTHER

Principal Investigators

  • Tiina Ojala, MD, PhD · Helsinki University Hospital, Finland

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-07
Primary Completion
2022-03-07
Completion
2024-03-07

Countries

  • Finland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04311346 on ClinicalTrials.gov